Latest publications

The use of single armed observational data to closing the gap in otherwise disconnected evidence networks: a network meta-analysis in multiple myeloma.

  • Competence Center for Methodology and Statistics
June 28, 2018
2018 Jun. BMC Med Res Methodol.18(1):66.
By:
  • Schmitz S
  • Maguire A
  • Morris J
  • Ruggeri K
  • Haller E
  • Kuhn I
  • Leahy J
  • Homer N
  • Khan A
  • Bowden J
  • Buchanan V
  • O'Dwyer M
  • Cook G
  • Walsh C.

Marketing authorisation applications submitted to the European Medicines Agency by small and medium-sized enterprises: an analysis of major objections and their impact on outcomes.

  • Competence Center for Methodology and Statistics
June 25, 2018
2018 Jun. Drug Discov Today.23(10):1801-1805. Epub 2018 Jun 25.
By:
  • Amaouche N
  • Casaert Salome H
  • Collignon O
  • Santos MR
  • Ziogas C.

Geographical variation of overweight, obesity and related risk factors: Findings from the European Health Examination Survey in Luxembourg, 2013-2015.

  • Competence Center for Methodology and Statistics
  • Clinical and Epidemiological Investigation Center
June 14, 2018
2018 Jun. PLoS One.13(6):e0197021.
By:
  • Samouda H
  • Ruiz-Castell M
  • Bocquet V
  • Kuemmerle A
  • Chioti A
  • Dadoun F
  • Kandala NB
  • Stranges S.

Childhood asthma exacerbations and ADRB2 polymorphism: Caution is needed.

  • Competence Center for Methodology and Statistics
May 18, 2018
2018 May. J Allergy Clin Immunol.141(5):1954-1955. Epub 2018 Mar 6.
By:
  • Senn S.

Statistical analysis plans for clinical trials—reply.

  • Competence Center for Methodology and Statistics
May 08, 2018
2018 May. JAMA.319(18):1938-1939.
By:
  • Gamble C
  • Lewis S
  • Senn S.

Statistical considerations about the design and endpoints of randomized clinical trials for children with irritable bowel syndrome.

  • Competence Center for Methodology and Statistics
May 01, 2018
2018 May. Neurogastroenterol Motil.30(5):e13266.
By:
  • Collignon O
  • Petavy F.

Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: A systematic review, meta-analysis and individual patient data analysis.

  • Competence Center for Methodology and Statistics
April 27, 2018
2018 Apr. PLoS Negl Trop Dis.12(4):e0006458.
By:
  • Palmeirim MS
  • Hurlimann E
  • Knopp S
  • Speich B
  • Belizario V
  • Joseph SA
  • Vaillant M
  • Olliaro P
  • Keiser J.

Requirements for certification of ECRIN data centres, with explanation and elaboration of standards, Version 4.0. (Book)

  • Clinical and Epidemiological Investigation Center
April 27, 2018
2018 Apr. Genève: Zenodo, 2018. 107 p.
By:
  • Canham S
  • Alex Bernalte G
  • Crocombe W
  • De Bremaeker N
  • Domingues C
  • Faherty M
  • Garcia Morales MT
  • Houston L
  • Lauritsen J
  • Nicolis EB
  • Ohmann C
  • Pham C
  • Ruckes C
  • Toneatti C
  • Wittenberg M.

Reply-Letter to the Editor - Smoking status is inversely associated with overall diet quality: Findings from the ORISCAV-LUX study.

  • Competence Center for Methodology and Statistics
April 01, 2018
2018 Apr. Clin Nutr.37(2):761-762. Epub 2018 Feb 15.
By:
  • Alkerwi A
  • Baydarlioglu B
  • Sauvageot N
  • Stranges S
  • Lemmens P
  • Shivappa N
  • Hebert JR.

Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial.

  • Competence Center for Methodology and Statistics
April 01, 2018
2018 Apr. Lancet Infect Dis.18(4):419-430. Epub 2018 Jan 16.
By:
  • Torrico F
  • Gascon J
  • Ortiz L
  • Alonso-Vega C
  • Pinazo M-J
  • Schijman A
  • Almeida IC
  • Alves F
  • Strub-Wourgaft N
  • Ribeiro I
  • Santina G
  • Blum B
  • Correia E
  • Garcia-Bournisen F
  • Vaillant M
  • Morales JR
  • Pinto Rocha JJ
  • Rojas Delgadillo G
  • Magne Anzoleaga HR
  • Mendoza N
  • Quechover RC
  • Caballero MYE
  • Lozano Beltran DF
  • Zalabar AM
  • Rojas Panozo L
  • Palacios Lopez A
  • Torrico Terceros D
  • Fernandez Galvez VA
  • Cardozo L
  • Cuellar G
  • Vasco Arenas RN
  • Gonzales I
  • Hoyos Delfin CF
  • Garcia L
  • Parrado R
  • de la Barra A
  • Montano N
  • Villarroel S
  • Duffy T
  • Bisio M
  • Ramirez JC
  • Duncanson F
  • Everson M
  • Daniels A
  • Asada M
  • Cox E
  • Wesche D
  • Diderichsen PM
  • Marques AF
  • Izquierdo L
  • Sender SS
  • Reverter JC
  • Morales M
  • Jimenez W.

Comparative analysis of the association between 35 frailty scores and cardiovascular events, cancer, and total mortality in an elderly general population in England: An observational study.

  • Competence Center for Methodology and Statistics
March 27, 2018
2018 Mar. PLoS Med.15(3):e1002543.
By:
  • Aguayo GA
  • Vaillant MT
  • Donneau AF
  • Schritz A
  • Stranges S
  • Malisoux L
  • Chioti A
  • Guillaume M
  • Muller M
  • Witte DR.

Neoadjuvant treatment for malignant and metastatic cutaneous melanoma.

  • Competence Center for Methodology and Statistics
March 09, 2018
2018 Mar. Cochrane Database Syst Rev.2018(3).
By:
  • Gorry C
  • McCullagh L
  • O'Donnell H
  • Barrett S
  • Schmitz S
  • Barry M
  • Curtin K
  • Beausang E
  • Barry R
  • Coyne I.

Vers une recherche qui améliore notre santé et change les modes de vie. Pr Laetitia Huiart : nouvelle directrice du «Department of Population Health» du LIH.

  • Clinical and Epidemiological Investigation Center
March 01, 2018
2018 Mar. Semper Luxembourg.(100):18-19.
By:
  • Gantenbein M.

A multicentre, randomised, non-inferiority clinical trial comparing a nifurtimox-eflornithine combination to standard eflornithine monotherapy for late stage Trypanosoma brucei gambiense human African trypanosomiasis in Uganda.

  • Competence Center for Methodology and Statistics
February 22, 2018
2018 Feb. Parasit Vectors.11(1):105.
By:
  • Kansiime F
  • Adibaku S
  • Wamboga C
  • Idi F
  • Kato CD
  • Yamuah L
  • Vaillant M
  • Kioy D
  • Olliaro P
  • Matovu E.

European Health Interview Survey (EHIS): Utilisation et accessibilité des services de santé (Factsheet)

  • Competence Center for Methodology and Statistics
February 01, 2018
2018 Feb. Luxembourg: Ministère de la Santé – Direction de la Santé, Luxembourg Institute of Health, 2018. 2 p.
By:
  • Ruiz-Castell M
  • Barre J
  • Couffignal S.

L’économie de la santé au Luxembourg: la clé pour un système de soins de santé durable?

  • Competence Center for Methodology and Statistics
February 01, 2018
2018 Feb. Semper Luxembourg.(99):20-22.
By:
  • Schmitz S.

Social value and individual choice: The value of a choice-based decision-making process in a collectively funded health system.

  • Competence Center for Methodology and Statistics
February 01, 2018
2018 Feb. Health Econ.27(2):e28-e40. Epub 2017 Oct 4.
By:
  • Espinoza MA
  • Manca A
  • Claxton K
  • Sculpher M.

European Health Interview Survey (EHIS): Etat de santé et bien-être (Factsheet)

  • Competence Center for Methodology and Statistics
January 01, 2018
2018 Jan. Luxembourg: Ministère de la Santé – Direction de la Santé, Luxembourg Institute of Health, 2018. 2 p.
By:
  • Ruiz-Castell M
  • Barre J
  • Couffignal S.

Guidelines for the content of statistical analysis plans in clinical trials.

  • Competence Center for Methodology and Statistics
December 19, 2017
2017 Dec. JAMA.318(23):2337-2343.
By:
  • Gamble C
  • Krishan A
  • Stocken D
  • Lewis S
  • Juszczak E
  • Dore C
  • Williamson PR
  • Altman DG
  • Montgomery A
  • Lim P
  • Berlin J
  • Senn S
  • Day S
  • Barbachano Y
  • Loder E.

Proinflammatory T cell status associated with early life adversity.

  • Competence Center for Methodology and Statistics
December 15, 2017
2017 Dec. J Immunol.199(12):4046-4055. Epub 2017 Nov 13.
By:
  • Elwenspoek MMC
  • Hengesch X
  • Leenen FAD
  • Schritz A
  • Sias K
  • Schaan VK
  • Meriaux SB
  • Schmitz S
  • Bonnemberger F
  • Schachinger H
  • Vogele C
  • Turner JD
  • Muller CP.