Lecture Series Translational Bioinformatics & Systems Biomedicine - "TRANSLATING SYSTEMS BIOLOGY-BASED SIGNATURES AS PROGNOSTIC CANCER BIOMARKERS AND STRATIFICATION TOOLS" - Prof Jochen Prehn
27/09/2018 16:00 to 27/09/2018 18:30 (Europe/Luxembourg)
Speaker
Prof Jochen Prehn is Professor of Physiology & Director, Centre for Systems Medicine, Royal College of Surgeons in Ireland.
Abstract
Professor Prehn is considered an international authority on the single-cell analysis and the molecular control of apoptosis, cancer cell death, nerve cell death, as well as mitochondrial function and dysfunction. This research included the development of computational approaches to understand bio- energetics, apoptosis sensitivity and apoptosis resistance at a systems level. In collaboration with clinicians (pathology, medicine, and surgery), Prof Prehn translated these approaches into clinically relevant settings, and has initiated multiple large scale, multi-partner clinical projects such as the APO-COLON and APO-DECIDE clinical studies. In his presentation, Prof Prehn will highlight his recent research applying quantitative and systems-based analyses of BCL-2 signalling, caspase signalling and cellular bioenergetics pathways. These processes represent key downstream targets of oncogenic transformation. He will in particular showcase the application of dynamic systems modelling for the identification of novel prognostic biomarkers and stratification tools for the treatment of colorectal cancer (CRC) and other solid tumours.
schedule
16.00 - 17.00: LECTURE
University of Luxembourg
Maison des Sciences Humaines
11, Porte des Sciences
L-4366 Esch/Alzette
Blackbox room
17.00 - 18.30: 'meet THE SPEAKER'
University of Luxembourg
Maison des Sciences Humaines
11, Porte des Sciences
L-4366 Esch/Alzette
Room N°0.207
Registration required for the 'Meet the Speaker' - send us an email
programme 2017-2018
About the Lecture & Workshop series - TRANSLATIONAL BIOINFORMATICS AND SYSTEMS BIOMEDICINE
The LIH lecture and workshops series in Translational Bioinformatics and Systems Biomedicine, supported by the FNR and jointly organized with the University of Luxembourg, are gathering internationally
This lecture will be followed by a workshop especially dedicated to early-stage researchers.
Attendance to the lecture and workshop are free of charge. Should you be interested in registering for the workshop, please feel free to do so by sending us an email.