Lecture series Translational Bioinformatics and Systems Biomedicine "INTEGRATIVE NETWORK-BASED ANALYSIS FOR SUBTYPING AND CANCER DRIVER IDENTIFICATION" - Prof Kathleen Marchal
23/10/2018 16:00 to 23/10/2018 18:30 (Europe/Luxembourg)
Speaker
Prof Kathleen Marchal is Associate Professor, Dept of Plant Biotechnology and Bioinformatics, Faculty of Sciences; Dept of Information Technology (IDLab, IMEC), Faculty of Engineering, Ghent University, Ghent, Netherlands.
Abstract
Linking omics data of tumor samples with the patients’ clinical phenotype offers the potential to identify biomarkers and drug targets. Network-based approaches, which drive the genotype phenotype association by a prior molecular interaction network, are powerful data analysis strategies as they allow (1) dealing with small cohort sizes, (2) providing an intuitive scaffold for integrating multiple data sources in order to identify pathways that are recurrently hit by mutations, but also functionally affected by these mutations and (3) providing insight in the mechanism of the cancer-related phenotype. We will illustrate the power of fully integrated network models in prioritizing rare mutations that can be coupled to a functional and/or a clinical phenotype.
schedule
16.00 - 17.00: LECTURE
University of Luxembourg
Maison des Sciences Humaines
11, Porte des Sciences
L-4366 Esch/Alzette
Blackbox room
17.00 - 18.30: 'meet THE SPEAKER'
University of Luxembourg
Maison des Sciences Humaines
11, Porte des Sciences
L-4366 Esch/Alzette
Room N°0.207
Registration required for the 'Meet the Speaker' - send us an email
programme 2017-2018
About the Lecture & Workshop series - TRANSLATIONAL BIOINFORMATICS AND SYSTEMS BIOMEDICINE
The LIH lecture and workshops series in Translational Bioinformatics and Systems Biomedicine, supported by the FNR and jointly organized with the University of Luxembourg, are gathering internationally
This lecture will be followed by a workshop especially dedicated to early-stage researchers.
Attendance to the lecture and workshop are free of charge. Should you be interested in registering for the workshop, please feel free to do so by sending us an email.