Quality, but not quantity of physical activity is associated with metal ion concentrations in unilateral hip resurfacing.

October 01, 2020 By:
  • Jelsma J
  • Schotanus MGM
  • van Kuijk SMJ
  • Buil I
  • Heyligers IC
  • Grimm B.

Little is known about the influence of physical activity (PA) on metal ion concentrations in subjects with metal-on-metal hip arthroplasty. Implant wear is thought to be a function of use and thus of patient activity levels. It is hypothesized that daily habitual PA of patients with hip resurfacing arthroplasty (HRA) is associated with metal ion concentrations. Therefore a study was conducted in patients with a unilateral HRA at 10-years follow-up. Blood metal ion concentrations were determined. An acceleration-based activity monitor was used to measure PA in daily life. The cohort consisted of 12 males (75%) and 4 females (25%) with a median age at surgery of 55.5 +/- 9.7 years [43.0-67.9] and a median follow-up of 9.9 +/- 1.0 years [9.1-10.9]. The median cobalt and chromium ion concentrations were 25 +/- 13 and 38 +/- 28 nmol/L. A significant association between sit-stand transfers and high-intensity peaks with cobalt ion concentrations were found. Regarding PA and metal ion concentrations as a proxy of wear in HRA, specific activities like transfers or qualitative aspects of activity behavior like intensity, seem to matter more than the quantity of low-intensity activities like walking or cycling. This suggests that patients may safely engage in such activities to achieve important general health benefits and quality of life.

2020 Oct. J Orthop Res.38(10):2206-2212. Epub 2020 Mar 2.
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