Preservation of biospecimens at ambient temperature: Special focus on nucleic acids and opportunities for the biobanking community.

April 01, 2016 By:
  • Muller R
  • Betsou F
  • Barnes MG
  • Harding K
  • Bonnet J
  • Kofanova O
  • Crowe JH
  • International Society for Biological Environmental Repositories (ISBER) Biospecimen Science Working Group.

Several approaches to the preservation of biological materials at ambient temperature and the relative impact on sample stability and degradation are reviewed, with a focus on nucleic acids. This appraisal is undertaken within the framework of biobank risk, quality management systems, and accreditation, with a view to assessing how best to apply ambient temperature sample storage to ensure stability, reduce costs, improve handling logistics, and increase the efficiency of biobank procedures.

2016 Apr. Biopreserv Biobank.14(2):89-98. Epub 2016 Feb 17.
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