Designing noninferiority tuberculosis treatment trials: Identifying practical advantages for drug regimens with acceptable effectiveness.

  • Competence Center for Methodology and Statistics
July 12, 2019 By:
  • Olliaro PL
  • Vaillant M.

In this Collection Review for the Novel Treatments for Tuberculosis Collection, Piero Olliaro and Michael Vaillant discuss the considerations when choosing a non-inferiority margin that is meaningful from statistical, ethical, clinical, and health standpoint.

2019 Jul. PLoS Med.16(7):e1002850.
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