Blood Pressure Drop Prediction by using HRV Measurements in Orthostatic Hypotension.

November 01, 2015 By:
  • Sannino G
  • Melillo P
  • Stranges S
  • Pietro GD
  • Pecchia L.

Orthostatic Hypotension is defined as a reduction of systolic and diastolic blood pressure within 3 minutes of standing, and may cause dizziness and loss of balance. Orthostatic Hypotension has been considered an important risk factor for falls since 1960. This paper presents a model to predict the systolic blood pressure drop due to orthostatic hypotension, relying on heart rate variability measurements extracted from 5 minute ECGs recorded before standing. This model was developed and validated with the leave-one-out cross-validation technique involving 10 healthy subjects, and finally tested with an additional 5 healthy subjects, whose data were not used during the training and cross-validation process. The results show that the model predicts correctly the systolic blood pressure drop in 80 % of all experiments, with an error rate below the measurement error of a sphygmomanometer digital device.

2015 Nov. J Med Syst.39(11):292. Epub 2015 Sep 7.
Other information